UCSC

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library(rtracklayer)
library(AnnotationHub)

# 第一次会下载 
ah <- AnnotationHub()

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ah

# C:/Users/DELL/AppData/Local/R/cache/R/AnnotationHub/

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OrgDb_Human <- subset(ah, rdataclass == "OrgDb" & species == "Homo sapiens")
OrgDb_Human

org <- OrgDb_Human[[1]]
org

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GRanges_Human <- subset(ah, rdataclass == "GRanges" & species == "Homo sapiens")

gr <- GRanges_Human[1]
gr